It’s already gameweek 2 in the Premier League, and we have some big games this week, as Newcastle United will host Liverpool in an anticipated matchup at St. James’ Park this Monday. This will be the fourth encounter between Eddie Howe and Arne Slot, as they split three matches last season with one win each and a draw.
Things have heated up between Newcastle and Liverpool recently because of Alexander Isak’s situation, so what can we expect from this matchup?
| Tournament: | English Premier League season 2025-26, Matchday 2 |
| ⚽️ Venue: | St. James’ Park, Newcastle, England |
| 🗓️ Date: | 25 August 2025 |
| ⏰ Time: | 7 p.m. GMT on Monday |
Latest professional football odds show that Newcastle United are the slight home underdogs at 3.30 (23/10). A draw is offered at 3.80 (14/5), while Liverpool are the favorites at 2.10 (11/10) to beat the Magpies in this tough matchup at St. James’ Park.
The Magpies have been one of the Reds’ most favorite opponents in the last few years. In the last 16 head-to-head games, Liverpool won 12, drew three, and Newcastle United won only once, but made it in the Carabao Cup 2025 final.
Newcastle United are sitting in 12th place in the Premier League after the first game of the season. The Magpies completed the signing of Jacob Ramsey from Aston Villa this week, and he is expected to have his debut with the team against Liverpool. Newcastle are currently on a nine-game winless streak, but they have a favorable run of fixtures after this one.
The Magpies are coming off a 0-0 away draw with Aston Villa in the Premier League. The EPL best bookmakers had them as slight underdogs in that game, but they were much better than the Villans due to Ezri Konsa’s red card. Newcastle had 1.44 expected goals (xG) compared to Villa’s 0.20, and their new signing, Anthony Elanga, looked sharp in that game.
Newcastle United are still missing Joe Willock due to a long-term injury, while Alexander Isak is out due to the coach’s decision.
Liverpool are currently fourth in the Premier League standings after matchday 1. The Reds are the EPL’s defending champions, and they have made some big signings this pre-season, acquiring some quality players like Florian Wirtz, Hugo Ekitike, Jeremie Frimpong, and Milos Kerkez. Liverpool lost the Community Shield game to Crystal Palace on penalties last week.
However, the Reds are coming off a big 4-2 home win over Bournemouth in the Premier League. Hugo Ekitike, Cody Gakpo, Federico Chiesa, and Mohamed Salah scored the winning goals for the team. The Cherries almost came back from a 2-0 deficit, but Liverpool were clutch in the last 10 minutes. That was Chiesa’s first EPL goal for the Reds.
Liverpool will miss Jeremie Frimpong until the international break with a hamstring injury, while Conor Bradley is doubtful, and Ryan Gravenberch is back and ready.
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The Reds always play well against Newcastle, as they have lost only twice to the Magpies in their last 20 games. Newcastle didn’t have the best pre-season, losing four games and drawing two, and they followed that with a draw against Aston Villa’s 10 men.
The English Premier League odds mark Liverpool as favorites in this game are really worth considering, as they have looked sharper and more ready than Newcastle at the start of the season. This is a revenge game for the Reds after losing the 2025 EFL Cup final to the Magpies, while the hosts will be without their biggest offense threat in the face of Isak.
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Liverpool’s first two games of the season suggest that their matches will be more open than before, as Crystal Palace’s game had four goals and Bournemouth’s game had six. The Reds are still vulnerable at the back, and they have a great offense, so they will rely on outscoring Newcastle. Four of the last five head-to-head games between the teams had over 2.5 goals, and both of them scored.
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Mohamed Salah has a great record against Newcastle in the Premier League with the Reds, beating them in 12 games and drawing four with no losses, and he scored 10 goals in addition to eight assists in those matches. The Egyptian scored a goal in the opening fixture, as always, and he is in great spirits after winning his third PFA Player of the Year Award last week, becoming the first-ever player to do so. Newcastle’s defense isn’t at its best right now, so Salah will be aiming to take advantage of that.
The Reds gave the Magpies a hard time in the last few years, and we expect them to get the win on Monday as well. Make sure you use our 2025 Newcastle vs Liverpool betting predictions and bet them at the legal bookmakers in the UK to have more fun watching the game.
