We are back to the Premier League race after exciting midweek Champions League action. Liverpool will host Everton in the Merseyside derby this Saturday afternoon at Anfield, as the Reds are coming from another late-winning game against Atletico Madrid. This will be the third encounter between Arne Slot and David Moyes.
Liverpool and Everton have both started the EPL season very well, so what can we expect from this big clash?
| ℹ️ Tournament: | English Premier League season 2025-26, Matchday 5 |
| ⚽️ Venue: | Anfield Stadium, Liverpool, England |
| 🗓️ Date: | 20 September 2025 |
| ⏰ Time: | 11:30 a.m. GMT on Saturday |
If you want to check the best odds on football, then we have a quick numbered look for this game just here. Liverpool are the big home favorites at 1.45 (9/20). A draw is offered at 4.80 (19/5), while Everton are the underdogs at 6.50 (11/2) to beat the Reds at Anfield.
The Reds have absolutely dominated the Merseyside derby recently, as in the last 15 head-to-head games, Liverpool won eight, drew five, and Everton won only twice.
Liverpool are on top of the Premier League standings with the full 12 points from four games. The Reds sit 7th in the UCL league phase after one match, and they will face Southampton in the EFL round of 32 next Tuesday.
The Reds are coming off a thrilling 3-2 home win over Atletico Madrid in the UCL. Mohamed Salah, Andy Robertson, and Virgil van Dijk scored the winning goals for the team. The betting odds on the Premier League have Liverpool as bigger favorites to win the title now, especially after signing Alexander Isak, and they are already three points above the second-place team after three rounds.
Liverpool have a full squad for this game, as they are only missing Curtis Jones, while everyone else is fine and ready, including Alexander Isak.
Everton are currently in 7th place in the Premier League standings with seven points. The Toffees had a much better start to the season than expected, and they also beat Mansfield in the EFL Cup and will face Wolves in the round of 32. Everton had four extra rest days compared to Liverpool, as they didn’t play any competitions midweek.
The Toffees are coming off a 0-0 home draw with Aston Villa in the Premier League. Everton were much better in that game, especially offensively, having 20 shots compared to Villa’s seven, and they had 2.08 expected goals, while Villa had only 0.54. The Toffees beat Liverpool at Anfield only once in the last 25 years.
Everton are still missing Jarrad Branthwaite due to a long-term injury, while Vitalii Mykolenko is doubtful for this game.
1 (50%)
(50%) 1
The best bookies for the EPL have offered a massive variety of betting options, but we consider the odds on Alexander Isak to score in this game pretty attractive. The Swedish striker will make his EPL debut with the Reds in this game, and there’s nothing better than scoring in the Merseyside derby in your first match. Isak played 60 minutes against Atletico Madrid on Wednesday, and he had two shots and 0.53 expected assists (xA), so he is fit and will be motivated to score in the derby, but make sure that he is in the starting lineup first to avoid any surprises.
2 (100%)
0
The Merseyside derby is known for producing a lot of low-scoring matches lately, as they have gone under the total in six of their last seven head-to-head games, averaging only 1.85 goals per game. The Toffees still have a good defense this season, as they have only conceded three goals in five games in all competitions so far, and they have gone under the total in five of their last six matches.
2 (100%)
0
This game will be tense as it has always been with the Merseyside derby, and it will most likely have many cards as well. James Tarkowski is a player who gets booked a lot, as he has averaged 8.3 cards in the last seven EPL seasons, and he is due for a card after not getting any this season so far. The English defender got booked in his last two visits to Anfield, and he will be up against a fast offense that will cause him trouble.
It’s hard to pick the Reds to win this game with such low odds, but we think Alexander Isak will have a good chance to score. Make sure you use our 2025 Liverpool vs Everton betting predictions and bet them at the legal bookmakers in the UK to have more fun watching the game.
